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Mother-of-two Amanda Duncan has been missing since July 1993.
Amanda was 26 when she went missing from the Portman Road area of Ipswich on the night of Friday 2 July.
It is believed that the single mum, from Balliol Close, Woodbridge, had been working in the red light district.
She left two sons - Jamie and Damien - who were aged three years and nine months respectively at the time of her disappearance.
No one has heard from Amanda since she went missing, despite intensive local and national publicity.
Police are concerned that Amanda may have come to harm, however no evidence has ever been uncovered to show that she was the victim of an abduction or attack.
Amanda’s disappearance remains a mystery and is still an open case.
All new information relating to the case will be fully investigated. Amanda is white, 5ft 7ins tall, of medium build, with fair hair.
She has a distinctive heart-shaped tattoo on her upper arm.
Anyone with information is asked to contact Suffolk Police on 101 or call Crimestoppers anonymously 0800 555 111.